![]() ![]() ![]() Bauer, M.D., director of the Complementary and Integrative Medicine Program at the Mayo Clinic in Minnesota. "I have many women patients who have tried black cohosh," said Brent A. Compared to black cohosh, hormone therapy significantly reduced hot flash frequency. There was no significant difference between it and the placebo groups in changing hot flash frequency. The reviewers found there was insufficient evidence to support the effectiveness of black cohosh for menopausal symptoms. Treatments for randomly assigned comparison groups included using placeboes, hormone therapy, red clover, or antidepressants. Study participants used an average daily oral preparation of 40 mg of black cohosh for an average of 23 weeks. ![]() Leach and his co-reviewer evaluated 16 studies involving 2,027 menopausal women. "I was a little surprised of the outcome of the review given the large number of perimenopausal women that use the herb across the globe for the management of menopausal symptoms, as well as the many manufacturers and therapists that promote the herb for this purpose," said lead reviewer Matthew Leach, Ph.D., a research fellow in the School of Nursing & Midwifery at the University of South Australia. ![]()
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